Sulindac sulfone is primarily investigated for its potential chemopreventive properties, particularly in the context of cancer research. Studies have shown that it may inhibit the growth of certain cancer cells, including those in colorectal and prostate cancers, by inducing apoptosis and modulating signaling pathways. Its anti-inflammatory properties also make it a subject of interest for reducing inflammation-related cellular damage. Additionally, it has been explored for its role in neurodegenerative diseases due to its ability to reduce oxidative stress and inflammation in neural tissues. Research continues to explore its therapeutic potential in various medical fields.