Siramesine hydrochloride
10mM in DMSO
Reagent
Code: #233790
CAS Number
224177-60-0
blur_circular Chemical Specifications
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Molecular Information
Weight
491.04 g/mol
Formula
C₃₀H₃₁FN₂O.HCl
thermostat
Physical Properties
Melting Point
225 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in scientific research as a sigma receptor antagonist, particularly targeting sigma-2 receptors. It has been investigated for its potential in oncology due to its ability to induce apoptosis in cancer cells, especially in breast, lung, and glioma models. Shows activity in promoting lysosomal membrane permeabilization, leading to cell death, making it a compound of interest in developing new anticancer therapies. Also utilized as a pharmacological tool to study sigma receptor function in neurological and psychiatric conditions, though it has not advanced to clinical use in humans.
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