PND-1186 is primarily used as a research compound in the study of integrin signaling pathways, particularly targeting αvβ3 and αvβ5 integrins. It serves as a potent inhibitor of cell adhesion and migration, making it valuable in cancer research, especially in investigations related to tumor angiogenesis and metastasis. Due to its ability to block integrin-mediated interactions, it is utilized in preclinical studies to assess the impact of integrin inhibition on tumor growth and vascular development. Additionally, PND-1186 has been explored for its potential in modulating inflammatory responses and in the development of targeted therapies for diseases involving abnormal blood vessel formation. Its application remains largely confined to laboratory and experimental settings.