Used in research and development of cancer immunotherapies, particularly targeting tumors that overexpress L1-CAM, such as ovarian, endometrial, and colorectal cancers. The Fc tag enables easy detection and purification, and enhances stability in biological assays. It serves as a critical reagent in studying cell adhesion, neural development, and tumor metastasis. Commonly used in ELISA, flow cytometry, and antibody screening to evaluate binding interactions and therapeutic antibody candidates. Also employed in structural studies to understand L1-CAM-mediated signaling pathways.