Used in research and development of targeted cancer therapies, particularly for tumors overexpressing folate receptor alpha (FOLR1), such as ovarian, lung, and breast cancers. The Fc tag enables easy detection, purification, and extended serum half-life when used in immunoassays or as a capture agent in binding studies. It serves as a critical reagent in developing monoclonal antibodies, antibody-drug conjugates (ADCs), and diagnostic tools by mimicking the natural receptor-ligand interaction. Also employed in flow cytometry, ELISA, and protein-protein interaction assays to study immune responses and receptor binding mechanisms.