FB23-2(FTO Demethylase inhibitor FB23-2)
10mM in DMSO
Reagent
Code: #186815
CAS Number
2243736-45-8
blur_circular Chemical Specifications
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Molecular Information
Weight
392.236 g/mol
Formula
C₁₈H₁₅Cl₂N₃O₃
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Storage & Handling
Storage
-20°C
description Product Description
Used in epigenetic research to inhibit FTO (fat mass and obesity-associated) demethylase activity, specifically targeting the removal of N6-methyladenosine (m6A) modifications in RNA. This inhibition helps regulate gene expression by stabilizing m6A marks, making it a valuable tool in studying RNA methylation's role in cellular processes such as differentiation, metabolism, and cancer progression. Shows potential in leukemia research due to FTO's involvement in oncogenic signaling pathways. Also employed in developing therapeutic strategies where modulation of RNA demethylation may have clinical benefits.
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