DEL-22379 is primarily used in biochemical and pharmaceutical research as a selective inhibitor of protein-protein interactions, particularly targeting the p53-MDM2 interaction. This makes it a valuable tool in cancer research, where restoring p53 activity can trigger apoptosis in tumor cells. It is commonly applied in cellular assays to study pathways involved in cell cycle regulation and tumor suppression. Due to its ability to penetrate cell membranes effectively, DEL-22379 is often used in in vitro models to evaluate potential anticancer agents and to help identify downstream effects of p53 activation. Its role in early-stage drug discovery supports the development of novel therapeutics aimed at reactivating p53 in cancers where it is suppressed.