Used in research as a derivative of gliotoxin to study immunosuppressive and antifungal properties with reduced toxicity. Acts as a tool compound in cellular assays to probe thiol-dependent pathways and redox regulation. Investigated for its potential to modulate NF-κB signaling, which plays a role in inflammation and cancer. Also employed in studies exploring structure-activity relationships of epipolythiodioxopiperazine alkaloids.