BAM7
10mM in DMSO
Reagent
Code: #142532
CAS Number
331244-89-4
blur_circular Chemical Specifications
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Molecular Information
Weight
405.47 g/mol
Formula
C₂₁H₁₉N₅O₂S
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Registry Numbers
MDL Number
MFCD01246556
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Storage & Handling
Storage
-20°C
description Product Description
BAM7 is used in biochemical research as a selective activator of the pro-apoptotic protein BAX. It promotes BAX translocation to the mitochondria, triggering mitochondrial outer membrane permeabilization, which leads to caspase activation and programmed cell death. This makes BAM7 a valuable tool for studying apoptosis pathways, particularly in cancer research where modulating cell death is a key therapeutic strategy. It is also employed to investigate the role of BAX in cellular stress responses and mitochondrial function. Due to its specific mechanism, BAM7 helps in validating BAX as a drug target and in screening compounds that modulate BAX activity.
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