Mcl1-IN-1 is primarily utilized in research focused on cancer therapy. It functions as a potent inhibitor of Mcl-1, a protein that plays a critical role in preventing apoptosis in cancer cells. By inhibiting Mcl-1, this compound promotes programmed cell death in malignant cells, making it a valuable tool in studies aimed at developing targeted cancer treatments. Researchers use Mcl1-IN-1 to explore its efficacy in overcoming drug resistance, particularly in cancers where Mcl-1 overexpression contributes to survival and resistance to conventional therapies. Its application extends to preclinical studies, where it helps in understanding the mechanisms of apoptosis and evaluating potential therapeutic strategies for various cancers, including leukemia, lymphoma, and solid tumors.