SJG-136 is primarily utilized in the field of oncology as a potent antitumor agent. It functions by binding to the DNA of cancer cells, causing cross-links that prevent the DNA from unwinding and replicating. This mechanism effectively halts the proliferation of cancer cells, making it a valuable component in chemotherapy regimens, particularly for treating resistant or refractory cancers. Its targeted action on DNA also minimizes damage to healthy cells, reducing the severity of side effects commonly associated with traditional chemotherapy. Ongoing research explores its potential in combination therapies to enhance efficacy and broaden its application to various cancer types.