Fumagillol is primarily used in research and development for its potential anti-angiogenic properties. It has been studied for its ability to inhibit the formation of new blood vessels, which is crucial in the treatment of diseases like cancer, where tumor growth relies on angiogenesis. Additionally, it has been explored for its potential in treating conditions such as obesity and metabolic disorders due to its impact on fat cell formation. Researchers are also investigating its role in combating parasitic infections, leveraging its biological activity to disrupt the life cycle of certain parasites. Its derivatives are of particular interest in the development of novel therapeutic agents.