IR-780 iodide is widely used in biomedical imaging due to its near-infrared (NIR) fluorescence properties. It serves as a contrast agent for in vivo imaging, enabling deep tissue penetration and high-resolution visualization of tumors and other biological structures. Its lipophilic nature allows it to accumulate in cancer cells, making it valuable for cancer diagnosis and monitoring. Additionally, IR-780 iodide is employed in photothermal therapy, where it absorbs NIR light and converts it into heat to selectively destroy cancer cells. It is also utilized in drug delivery systems, where it helps track the distribution and efficacy of therapeutic agents. Furthermore, its application extends to the study of cellular processes and molecular interactions in research settings.