FC131 TFA is widely used in biomedical research, particularly in the development and testing of targeted cancer therapies. It functions as a high-affinity ligand for the chemokine receptor CXCR4, which plays a key role in tumor metastasis and cancer cell migration. Due to this specificity, FC131 TFA is employed in imaging studies to track CXCR4 expression in tumors using techniques such as PET or fluorescence imaging. It is also utilized in drug delivery systems where selective targeting of CXCR4-positive cells is required. Additionally, FC131 TFA serves as a valuable tool in in vitro and in vivo studies to block CXCR4 signaling, helping researchers understand the receptor’s role in cancer progression and immune cell trafficking. Its trifluoroacetate salt form enhances solubility and stability, making it suitable for biological assays.