4-Aminobutyl-DOTA
95%
Reagent
Code: #137890
CAS Number
753421-63-5
blur_circular Chemical Specifications
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Molecular Information
Weight
474.55 g/mol
Formula
C₂₀H₃₈N₆O₇
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used in nuclear medicine for radiolabeling peptides and proteins, enabling targeted imaging and therapy. Its structure allows stable complexation with radioactive metal ions like Gallium-68, Lutetium-177, or Yttrium-90, making it valuable in PET imaging and cancer treatments such as peptide receptor radionuclide therapy (PRRT). Commonly conjugated to biomolecules for precise tumor targeting, especially in neuroendocrine tumors and prostate cancer. Also employed in developing diagnostic agents due to high chelate stability and in vivo robustness.
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