CB-6644 is primarily studied for its potential in cancer therapy. It functions as an inhibitor of the RUVBL1/2 complex, which plays a critical role in chromatin remodeling and cellular processes such as DNA repair and transcription. By targeting this complex, CB-6644 disrupts cancer cell proliferation and survival, making it a promising candidate for treating various malignancies, particularly those resistant to conventional therapies. Research is ongoing to explore its efficacy in preclinical models and its potential use in combination with other anticancer agents.