CAY-10506 (also known as AS-252424) is a potent and selective inhibitor of phosphoinositide 3-kinase gamma (PI3Kγ), a key enzyme in cellular signaling pathways. It is primarily used in research settings to study its effects on cellular processes, particularly in the context of cancer biology, inflammation, and immune responses. By specifically inhibiting PI3Kγ, it disrupts lipid kinase activity crucial for tumor growth, survival, immune cell activation, and inflammatory signaling, making it a valuable tool for understanding disease mechanisms and developing potential therapeutic strategies. Researchers utilize this compound to explore its impact on cell proliferation, apoptosis, metastasis, cytokine production, and neutrophil migration in various cancer and inflammatory models. Additionally, it may be employed in preclinical studies to assess its efficacy, selectivity, and safety as a potential anticancer or anti-inflammatory agent. Its application extends to investigating the role of PI3Kγ-targeted pathways in other diseases, such as autoimmune disorders and cardiovascular conditions, contributing to broader biomedical research efforts.