Verucopeptin is a natural depsipeptide compound isolated from the bacterium Streptomyces sp., known for its antimicrobial properties against Gram-positive bacteria and fungi. It exhibits a unique mechanism of action by inhibiting cell wall synthesis or related processes, making it effective against certain infections. Additionally, research has explored its potential in cancer therapy due to its ability to inhibit specific enzymes or proteins involved in cell proliferation, disrupting cancer cell growth and survival. Ongoing studies aim to develop it as a therapeutic agent for both infectious diseases and oncology, particularly where conventional treatments are limited, while optimizing its selectivity and minimizing side effects.