This compound, UAMC-3203 free base, is a potent and selective inhibitor of MALT1 protease, which plays a key role in NF-κB signaling. It is primarily utilized in research settings for targeting aberrant immune responses in oncology, particularly B-cell lymphomas like diffuse large B-cell lymphoma (DLBCL). Preclinical studies have shown promise in understanding cellular mechanisms of cancer cell survival and proliferation, aiding the development of therapeutic strategies. Additionally, its application extends to biochemical assays for elucidating protein interactions and signaling pathways. Researchers also explore its use in pharmacological studies to assess efficacy and safety for future drug development.