GOT1 inhibitor 2c is primarily used in research focused on cancer metabolism, particularly in targeting glutamine metabolism pathways. By inhibiting GOT1, it disrupts the conversion of glutamine to aspartate, which is crucial for the survival and proliferation of certain cancer cells, especially those in pancreatic cancer. This compound helps in studying the metabolic vulnerabilities of cancer cells and exploring potential therapeutic strategies. Additionally, it serves as a tool to investigate the role of the malate-aspartate shuttle in cellular redox balance and energy production. Its application extends to understanding how metabolic reprogramming in cancer can be exploited for developing targeted treatments.