The Tn epitope is a carbohydrate antigen that plays a significant role in cancer research and immunotherapy. It is commonly found on the surface of cancer cells, particularly in carcinomas, and is associated with tumor progression and metastasis. Due to its overexpression in malignant tissues, the Tn epitope serves as a valuable biomarker for cancer diagnosis and monitoring. Researchers are actively exploring its potential in the development of cancer vaccines, as targeting this epitope can stimulate the immune system to recognize and destroy cancer cells. Additionally, the Tn epitope is being studied for its role in improving the specificity of antibody-based therapies, enabling more precise targeting of tumors while minimizing damage to healthy tissues. Its unique presence on cancer cells makes it a promising tool for advancing personalized cancer treatments and early detection strategies.