KN-62 is widely used in research to study calcium signaling pathways, particularly as a selective inhibitor of the calcium/calmodulin-dependent protein kinase II (CaMKII). It helps in understanding the role of CaMKII in various physiological and pathological processes, such as neuronal function, cardiac regulation, and memory formation. Researchers utilize KN-62 to investigate its effects on synaptic plasticity, learning, and memory in neurological studies. Additionally, it is employed in studies related to cardiovascular diseases, where CaMKII plays a critical role in cardiac hypertrophy and arrhythmias. KN-62 is also a valuable tool in exploring potential therapeutic targets for conditions like stroke, epilepsy, and neurodegenerative disorders.