Used as a selective ionophore in ion-selective electrodes, particularly for detecting heavy metal ions such as lead (Pb²⁺) and cadmium (Cd²⁺) in environmental and biological samples. Its structure allows selective binding of specific cations due to preorganized cavity and functional side arms. Commonly applied in electrochemical sensors for monitoring water quality and industrial effluents. Also investigated in separation technologies for metal recovery and wastewater treatment due to its chelating properties. Shows potential in analytical chemistry for improving selectivity and sensitivity in potentiometric detection methods.