Used as a selective ionophore in ion-selective electrodes, particularly for detecting heavy metal ions such as lead (Pb²⁺) and cadmium (Cd²⁺) in environmental and biological samples. Its rigid cup-shaped structure allows for effective host-guest interactions, enhancing sensor sensitivity and selectivity. Also employed in supramolecular chemistry for molecular recognition and sensing applications due to its ability to form stable complexes with cations and neutral molecules. Shows potential in separation technologies for removing toxic metal ions from wastewater.