GV-58 is primarily utilized in scientific research, particularly in the study of ion channels and cellular signaling pathways. It acts as a potent and selective inhibitor of N-type calcium channels (Cav2.2), making it a valuable tool for investigating the role of these channels in various physiological processes. Researchers employ GV-58 to explore its effects on neurotransmitter release, pain signaling, and other cellular functions regulated by calcium signaling. Its specificity and efficacy in modulating N-type calcium channels contribute to its use in experimental studies aimed at understanding diseases related to calcium dysregulation, such as chronic pain, epilepsy, and other neurological disorders. Additionally, GV-58 serves as a reference compound in the development of new therapeutic agents targeting N-type calcium channels.