CGP37157 is primarily used in research settings to study cellular processes, particularly those involving calcium signaling. It is known to inhibit the mitochondrial sodium-calcium exchanger (mNCX), which plays a critical role in regulating calcium levels within cells. By blocking this exchanger, CGP37157 allows researchers to investigate the effects of disrupted calcium homeostasis on cellular functions, such as mitochondrial energy production, cell survival, and apoptosis. This compound is especially valuable in neuroscience research, where calcium dysregulation is linked to neurodegenerative diseases like Parkinson's and Alzheimer's. Additionally, CGP37157 is utilized in studies exploring the role of calcium in cardiac cells, providing insights into heart function and potential therapeutic targets for cardiovascular conditions. Its application helps advance understanding of calcium's role in various physiological and pathological processes.