Calcium glycolate is commonly used in the food and pharmaceutical industries as a source of calcium. It serves as a nutritional supplement in fortified foods and beverages, such as alternative milks, grain-based drinks, and ready-to-eat meals, helping to support bone health and prevent calcium deficiency. Due to its good solubility and bioavailability, it is preferred in some calcium-fortified products over less soluble calcium salts. It is also suitable for individuals with low stomach acid, as it does not require acid for absorption.

In pharmaceuticals, it is used in tablet and capsule formulations to deliver calcium in a form that is gentle on the stomach, making it suitable for individuals with sensitive digestive systems. It is also found in some oral rehydration and electrolyte replacement products.

Additionally, calcium glycolate finds use in certain dental products and oral care formulations, where it helps in reducing tooth sensitivity by supporting remineralization of enamel.

In the cosmetics industry, calcium glycolate plays a role in stabilizing products, sometimes used as a pH controller or to help strengthen the skin.

Furthermore, it is used in medical applications, such as in the production of biomaterials or bone-related coatings, due to its ability to release calcium slowly and safely to the body.

Its compatibility with other ingredients and mild nature make it a favorable choice in various health and wellness applications.