YM-58483 (BTP2) is primarily used in research to study calcium signaling pathways in cells. It acts as a selective inhibitor of CRAC (Calcium Release-Activated Calcium) channels, which are crucial for calcium entry in immune cells like T-cells and mast cells. By blocking these channels, it helps researchers understand the role of calcium in immune responses, inflammation, and cell activation. Additionally, it is used in preclinical studies to explore its potential therapeutic effects in autoimmune diseases, allergic reactions, and certain cancers where calcium signaling plays a key role. Its ability to modulate calcium influx makes it a valuable tool in cellular and molecular biology research.