(S)-Amlodipine
10mM in DMSO
Reagent
Code: #233969
CAS Number
103129-82-4
blur_circular Chemical Specifications
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Molecular Information
Weight
408.88 g/mol
Formula
C₂₀H₂₅ClN₂O₅
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Registry Numbers
MDL Number
MFCD09832686
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of hypertension and chronic stable angina, this compound functions as a calcium channel blocker, specifically targeting L-type calcium channels in vascular smooth muscle. It promotes vasodilation, reducing peripheral vascular resistance and lowering blood pressure. Due to its enantiomeric specificity, the (S)-enantiomer exhibits significantly greater potency in calcium channel blockade compared to the (R)-form, allowing for lower dosing and reduced side effects. It is commonly prescribed as a once-daily oral medication, offering sustained release and consistent blood levels over 24 hours. Its long half-life contributes to improved patient compliance and steady control of cardiovascular symptoms.
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