Used as a key intermediate in the synthesis of pharmaceuticals, particularly calcium channel blockers such as 1,4-dihydropyridine derivatives for treating hypertension. Its trans stereochemistry provides stability and specificity, aiding in the construction of vasodilatory structures that control calcium influx into vascular smooth muscle cells. The rigid cyclohexane backbone and positioned functional groups ensure specific stereochemistry. The ester and carboxylic acid groups allow for further chemical modifications, making it valuable in constructing complex molecules. Commonly employed in the preparation of biologically active compounds, including enzyme inhibitors and receptor modulators. Also utilized in the design of prodrugs where controlled hydrolysis of the ester group is required for activation.