Lomerizine Dihydrochloride

10mM in DMSO

Reagent Code: #201963
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CAS Number 101477-54-7

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scatter_plot Molecular Information
Weight 541.46 g/mol
Formula C₂₇H₃₀F₂N₂O₃·₂HCl
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MDL Number MFCD01703867
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used primarily in the treatment and prevention of migraine headaches, this compound acts as a calcium channel blocker, helping to reduce the frequency and severity of migraine episodes. It is believed to work by inhibiting excessive calcium influx into vascular and neuronal cells, particularly in the cerebral blood vessels, thereby stabilizing vascular tone and reducing cortical spreading depression—a key mechanism involved in migraines. Due to its selective action on cerebral vessels, it helps prevent vasospasm and improves cerebral blood flow without significantly affecting systemic blood pressure. It has also been explored for potential neuroprotective effects in conditions involving cerebral ischemia, though its main clinical use remains in migraine prophylaxis.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿5,900.00

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