Lomerizine Dihydrochloride
10mM in DMSO
Reagent
Code: #201963
CAS Number
101477-54-7
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
541.46 g/mol
Formula
C₂₇H₃₀F₂N₂O₃·₂HCl
badge
Registry Numbers
MDL Number
MFCD01703867
inventory_2
Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used primarily in the treatment and prevention of migraine headaches, this compound acts as a calcium channel blocker, helping to reduce the frequency and severity of migraine episodes. It is believed to work by inhibiting excessive calcium influx into vascular and neuronal cells, particularly in the cerebral blood vessels, thereby stabilizing vascular tone and reducing cortical spreading depression—a key mechanism involved in migraines. Due to its selective action on cerebral vessels, it helps prevent vasospasm and improves cerebral blood flow without significantly affecting systemic blood pressure. It has also been explored for potential neuroprotective effects in conditions involving cerebral ischemia, though its main clinical use remains in migraine prophylaxis.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB