Fendiline hydrochloride
10mM in DMSO
Reagent
Code: #186942
CAS Number
13636-18-5
blur_circular Chemical Specifications
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Molecular Information
Weight
351.91 g/mol
Formula
C₂₃H₂₅N·HCl
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Registry Numbers
MDL Number
MFCD00079301
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as a calcium channel blocker, it has been employed in the treatment of angina pectoris to improve myocardial oxygen supply by reducing cardiac workload. It helps in dilating coronary arteries, thereby increasing blood flow to the heart muscle. Additionally, it exhibits anti-arrhythmic properties, contributing to the stabilization of heart rhythm during ischemic conditions. Some studies have explored its potential as an adjuvant in cancer therapy due to its ability to modulate multidrug resistance in tumor cells by inhibiting P-glycoprotein, a drug efflux pump. It has also been investigated for its antiviral effects, particularly against certain enveloped viruses, by interfering with viral entry into host cells.
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