Efonidipine hydrochloride monoethanolate
10mM in DMSO
Reagent
Code: #181444
CAS Number
111011-76-8
blur_circular Chemical Specifications
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Molecular Information
Weight
714.1799999999999 g/mol
Formula
C₃₆H₄₅ClN₃O₈P
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of hypertension and angina pectoris, this compound acts as a calcium channel blocker that targets both L-type and T-type calcium channels. This dual blockade helps in reducing peripheral vascular resistance and improving coronary blood flow. It is particularly beneficial in patients with renal impairment, as it can help preserve kidney function while controlling blood pressure. Due to its vasodilatory effects, it also supports improved cardiac oxygen supply and reduced myocardial workload. The formulation with ethanol in the monoethanolate form enhances solubility and bioavailability, contributing to consistent therapeutic effects.
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