3-Benzyl 5-ethyl 6-methyl-2-phenyl-4-(phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate

98%

Reagent Code: #149596
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CAS Number 185222-90-6

science Other reagents with same CAS 185222-90-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 477.55 g/mol
Formula C₃₁H₂₇NO₄
badge Registry Numbers
MDL Number MFCD01867626
thermostat Physical Properties
Melting Point 155 - 156 ℃
Boiling Point 634.6 ℃ at 760 mmHg
inventory_2 Storage & Handling
Density 1.23±0.1 g/cm3(Predicted)
Storage -20 °C

description Product Description

Used as a key intermediate in the synthesis of calcium channel blockers, particularly in the development of dihydropyridine-based cardiovascular drugs. Its structure allows for selective modulation of L-type calcium channels, making it valuable in creating antihypertensive and antianginal agents. Commonly employed in research settings to design new derivatives with improved pharmacokinetic profiles. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to enhance potency and reduce side effects in next-generation heart medications.

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inventory 1mg
10-20 days ฿5,420.00

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3-Benzyl 5-ethyl 6-methyl-2-phenyl-4-(phenylethynyl)-1,4-dihydropyridine-3,5-dicarboxylate
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Used as a key intermediate in the synthesis of calcium channel blockers, particularly in the development of dihydropyridine-based cardiovascular drugs. Its structure allows for selective modulation of L-type calcium channels, making it valuable in creating antihypertensive and antianginal agents. Commonly employed in research settings to design new derivatives with improved pharmacokinetic profiles. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to enhance potency

Used as a key intermediate in the synthesis of calcium channel blockers, particularly in the development of dihydropyridine-based cardiovascular drugs. Its structure allows for selective modulation of L-type calcium channels, making it valuable in creating antihypertensive and antianginal agents. Commonly employed in research settings to design new derivatives with improved pharmacokinetic profiles. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to enhance potency and reduce side effects in next-generation heart medications.

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