Synta66 is primarily used in research settings to study and understand the mechanisms of calcium release-activated calcium (CRAC) channels. These channels play a crucial role in cellular processes, particularly in immune cell activation and function. By inhibiting CRAC channels, Synta66 helps researchers investigate the impact of calcium signaling on immune responses, inflammation, and related diseases. Its application is valuable in developing potential therapeutic strategies for conditions like autoimmune disorders, inflammatory diseases, and certain types of cancer, where CRAC channel activity is implicated. Additionally, Synta66 is utilized in pharmacological studies to explore its efficacy and specificity as a CRAC channel blocker, contributing to the broader field of ion channel research.