Norverapamil hydrochloride is primarily used in research settings to study calcium channel activity and its effects on cellular processes. It serves as a valuable tool in neuroscience and cardiovascular research, helping to understand the mechanisms of calcium channel blockers and their potential therapeutic applications. Additionally, it is utilized in pharmacological studies to explore its role in modulating neurotransmitter release and its impact on conditions like hypertension, arrhythmias, and migraines. Its application extends to investigating drug resistance in cancer cells, as calcium channels are implicated in tumor progression and chemotherapy resistance.