TE Buffer is widely used in molecular biology and biochemistry for the storage and dilution of nucleic acids, particularly DNA and RNA. Its primary application is to maintain the stability and integrity of these molecules by providing a suitable pH environment and chelating metal ions that could otherwise degrade the nucleic acids. It is commonly employed in techniques such as gel electrophoresis, PCR (polymerase chain reaction), and DNA/RNA extraction. Additionally, TE Buffer is used to resuspend DNA pellets after precipitation and to elute DNA from purification columns, ensuring the nucleic acids remain intact and functional for downstream applications. Its simplicity and effectiveness make it a staple in laboratories working with genetic material.