TE buffer is widely used in molecular biology and biochemistry for the storage and manipulation of DNA and RNA. It helps maintain the stability and integrity of nucleic acids by providing a suitable pH environment and chelating metal ions that could degrade the samples. It is commonly employed in techniques such as gel electrophoresis, PCR, and DNA/RNA extraction. TE buffer is also used to resuspend and dilute nucleic acids, ensuring they remain intact during experiments. Its consistent pH and ionic strength make it a reliable choice for long-term storage of DNA at -20°C. Additionally, TE buffer is often used in enzyme reactions to maintain optimal conditions without interfering with enzymatic activity.