TE Buffer is widely used in molecular biology for the storage and handling of DNA and RNA. It helps maintain the stability and integrity of nucleic acids by providing an optimal pH environment, typically around 8.0, which prevents degradation. The buffer is commonly utilized during DNA extraction, purification, and electrophoresis procedures. Additionally, TE Buffer is often employed in PCR (Polymerase Chain Reaction) preparations and as a diluent for DNA samples. Its ability to chelate metal ions also inhibits nucleases, ensuring the long-term preservation of genetic material.