TE buffer is widely used in molecular biology and biochemistry for the storage and handling of DNA and RNA. It helps maintain the stability of nucleic acids by preventing degradation, as the Tris component stabilizes the pH while EDTA chelates divalent cations that could otherwise activate nucleases. This buffer is commonly employed in procedures such as DNA extraction, gel electrophoresis, and PCR preparation. Additionally, TE buffer is used to resuspend and dilute nucleic acids, ensuring optimal conditions for enzymatic reactions and long-term storage. Its simplicity and effectiveness make it a staple in laboratories working with genetic material.