TE Buffer is widely used in molecular biology for the storage and dilution of DNA and RNA. Its primary application is to maintain the stability of nucleic acids by providing an optimal pH environment, 7.4 for this 50X concentrate, which helps prevent degradation. It is commonly employed in procedures such as gel electrophoresis, PCR, and other DNA/RNA manipulation techniques. Additionally, TE Buffer is used to resuspend DNA pellets after precipitation, ensuring the nucleic acids remain intact and functional for downstream applications. Its simplicity and effectiveness make it a staple in laboratories working with genetic material.