10X TE buffer (pH 8.5) is widely used in molecular biology for the storage and handling of DNA and RNA. It consists of Tris-HCl and EDTA, which provide a suitable pH environment and chelate metal ions to inhibit nucleases that could degrade nucleic acids. It is commonly employed in procedures such as gel electrophoresis, PCR, and DNA extraction. Additionally, TE buffer is used to resuspend DNA pellets and dilute nucleic acid samples without compromising their integrity. Its effectiveness in preserving DNA and RNA makes it a staple in laboratories focused on genetic research and biotechnology.