TE buffer is widely used in molecular biology for the storage and manipulation of DNA and RNA. It helps maintain the stability of nucleic acids by providing a suitable pH environment at 7.0, which is optimal for preventing degradation. The buffer is also used in various laboratory techniques such as gel electrophoresis, PCR, and DNA extraction, where it ensures the integrity of the genetic material. Additionally, TE buffer is employed in the preparation of samples for sequencing and cloning, as it minimizes the risk of enzymatic degradation by nucleases. Its simple composition and effectiveness make it a staple in molecular biology labs.