SPG buffer is widely used in molecular biology and virology for the stabilization and preservation of viral particles during laboratory procedures. It helps maintain the integrity and infectivity of viruses when collecting, storing, or transporting samples. Commonly used in vaccine development, SPG buffer prevents degradation of viral components by controlling pH and providing a protective environment. It is especially useful in studies involving viral titration, plaque assays, and in vivo infection models where maintaining viral activity is critical. Additionally, SPG buffer is employed in the purification and concentration of viruses, supporting efficient downstream analysis and experimentation.