Widely used in molecular biology workflows, this solution maintains RNA integrity by providing a stable, nuclease-free environment. It is essential in RNA isolation, purification, and storage to prevent degradation by RNases. Commonly used as a resuspension buffer for RNA samples, it ensures optimal performance in downstream applications such as RT-PCR, qPCR, RNA sequencing, and microarray analysis. Its nuclease-free formulation makes it ideal for sensitive enzymatic reactions including in vitro transcription and RNA transfection. Frequently used in cell lysis steps during RNA extraction protocols to inhibit RNase activity and preserve sample quality.