TES is widely used as a buffering agent in biochemical and molecular biology research due to its effective pH stabilization in the range of 6.8 to 8.2. It is particularly suitable for applications involving enzymes, cell cultures, and protein studies, as it does not interfere with biological processes or metal ion interactions. TES is commonly employed in electrophoresis, chromatography, and tissue culture media preparation. Its low toxicity and compatibility with various biochemical systems make it a preferred choice for maintaining stable pH conditions in experimental setups. Additionally, TES is used in the formulation of cosmetics and personal care products, where it helps maintain product stability and pH balance.