Siraganian Buffer is primarily used in immunological and biochemical research, particularly in studies involving mast cells and basophils. It is essential for maintaining the stability and functionality of these cells during experiments, ensuring accurate results in assays that measure histamine release or other cellular responses. The buffer's composition supports optimal cell viability and reactivity, making it a critical component in research focused on allergic reactions, immune responses, and inflammation. Its application extends to drug development, where it helps evaluate the efficacy of compounds targeting mast cell-mediated pathways. Additionally, it is utilized in diagnostic laboratories to study hypersensitivity reactions and understand the mechanisms underlying allergic diseases.