Sodium 1,2-ethanedisulfonate is a specialty chemical primarily used as an ion-pairing agent in reversed-phase liquid chromatography, such as HPLC, for the separation and analysis of ionic compounds, including anions and basic analytes. This high-purity grade (≥99%) ensures minimal interference in analytical methods. It forms stable ion pairs with charged species, enhancing peak shape and resolution in chromatographic separations. Additionally, due to its sulfonate groups, it exhibits chelating properties that can be applied in water treatment to sequester metal ions, and it may serve as a stabilizer or additive in select pharmaceutical and biochemical formulations requiring pH control or ionic modulation.