Sodium 2-hydroxyethanesulfonate (SHES), also known as sodium isethionate, is primarily utilized as a mild anionic surfactant in cosmetic and personal care products. It offers gentle cleansing, excellent foaming, and low irritation properties, making it suitable for sensitive skin formulations such as shampoos, body washes, and facial cleansers. In pharmaceutical applications, it acts as an emollient and stabilizer in topical formulations. Additionally, it serves as a chemical intermediate in the synthesis of other surfactants and compounds. Its biodegradable and water-soluble nature enhances its versatility in eco-friendly and pH-balanced product developments.