4-Bromo-3,3,4,4-tetrafluoro-1-butene is primarily used in the synthesis of fluorinated compounds, which are essential in various industrial applications. Its unique structure makes it a valuable intermediate in the production of specialty chemicals, particularly those requiring high thermal and chemical stability.

In the pharmaceutical industry, it serves as a building block for creating fluorinated drug candidates, enhancing their metabolic stability and bioavailability. Additionally, it is utilized in the development of advanced materials, such as fluoropolymers, which are known for their resistance to harsh environments, including extreme temperatures and corrosive chemicals.

This compound also finds applications in agrochemical research, where it is used to develop novel pesticides and herbicides with improved efficacy and environmental safety. Its role in organic synthesis further extends to the creation of fluorinated surfactants and coatings, which are critical in industries like electronics, automotive, and aerospace for their water and oil-repellent properties.